Modern Biophysical Chemistry

Detection and Analysis of Biomolecules

(Autor)

Buch | Softcover
360 Seiten
2014 | 2., aktualis. u. erg. Auflage
Wiley-VCH (Verlag)
978-3-527-33773-6 (ISBN)
71,90 inkl. MwSt
A brief introduction for readers with a background in biochemistry or biophysics to current technology for the analysis of proteins and other biomolecules, now in an updated and expanded edition that includes super-resolution microscopy and other novel methods.
Bridging the gap between general introductory texts and high-level handbooks, this second edition remains the best and most accessible source of knowledge for the latest in studying biomolecules with physical methods -- for training, teaching and self-study.

Completely updated and expanded, the new edition explains all relevant methods used in current industrial research, including such recent developments as super-resolution microscopy and imaging techniques. The text has been developed from a graduate course taught by the author for several years, and by presenting a mix of basic theory and real-life examples, he closes the gap between theory and experiment.

The first part, on basic biophysical chemistry, surveys fundamental spectroscopic techniques and properties that are the prerequisite for the more sophisticated technologies discussed later in the book. The second part covers the latest bioanalytical techniques based on physical methods, such as confocal fluorescence, ultrafast spectroscopy, optical tweezers, single molecule electrical measurements, quantum dots, and single molecule force microscopy. Both the text and illustrations have been prepared in a clear and accessible style, with exercises (and their solutions) accompanying each chapter.

The perfect addition to classic textbooks, this is only source for the really interesting stuff for spicing up standard biophysics courses. As a result, any reader with a basic understanding of biochemistry and/or biophysics will quickly gain an overview of the current technology used in the biophysical analysis of proteins, nucleic acids, and other biomolecules and their interactions.

"A fine introduction for physically oriented bioscientists at the graduate level or beyond" - Chemistry World.

Peter J. Walla is a group leader at the Max-Planck-Institute for Biophysical Chemistry in Göttingen (Germany), and Professor for Biophysical Chemistry at the University of Braunschweig. Having obtained his academic degrees from the Universities of Heidelberg and Göttingen, Professor Walla did postdoctoral research at the University of California at Berkeley, and headed a department in a Biotech company co-founded by Nobel Laureate Manfred Eigen, before taking up his current position.

Introduction: What is Biophysical Chemistry?

PART 1: BASIC METHODS IN BIOPHYSICAL CHEMISTRY
Basic Optical Principles
Optical Properties of Biomolecules
Basic Fluorescence Techniques
Chiroptical and Scattering Methods
Magnetic Resonance Techniques
Mass Spectrometry

PART 2: ADVANCED METHODS IN BIOPHYSICAL CHEMISTRY
Fluorescence Microscopy
Super-Resolution Fluorescence Microscopy
Single-Biomolecule Techniques
Ultrafast and Nonlinear Spectroscopy
Special Techniques
Assay Development, Readers and High-Throughput Screening

Erscheint lt. Verlag 6.8.2014
Verlagsort Weinheim
Sprache englisch
Maße 170 x 244 mm
Gewicht 717 g
Einbandart Paperback
Themenwelt Naturwissenschaften Biologie Biochemie
Naturwissenschaften Chemie Organische Chemie
Schlagworte Analytische Chemie • Biochemie • Biomolekül • Biophysikalische Chemie • Spektroskopie
ISBN-10 3-527-33773-3 / 3527337733
ISBN-13 978-3-527-33773-6 / 9783527337736
Zustand Neuware
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