Molecular Approaches to Heart Failure Therapy
Steinkopff (Verlag)
978-3-642-63332-4 (ISBN)
1 Alterations in excitation-contraction coupling and potential gene therapy targets in failing human hearts.- 2 Cardiac overexpression of fl-adrenergic receptors.- 3 Genetic approaches to elucidate the regulatory role of phospholamban in the heart.- 4 Manipulation of SERCA2a in the heart by gene transfer.- 5 Changing the cardiac calcium transient: SERCA2 overexpression versus phospholamban inhibition.- 6 Adenovirus-mediated gene transfer of SERCA isoforms.- 7 Overexpression of FKBP12.6 to influence SR function.- 8 Adenovirus-mediated myocardial gene therapy.- 9 Adenovirus-mediated transfection of multicellular cardiac preparations.- 10 Myocardial-specific gene delivery.- 11 Transfection studies using a new cardiac 3D gel system.- 12 Cellular mechanisms of cardiac arrhythmias - do they play a role in heart failure?.- 13 Potassium channel overexpression.- 14 Mechanisms and relevance of apoptosis.- 15 Strategies to prevent apoptosis.- 16 Neurohumoral modulation of metalloproteinases in cardiac failure:impact on remodeling.- 17 Oxidative stress in heart failure.- 18 Modulation of cardiac function by essential myosin light chains in health and disease.- 19 Myocardial infarction, infarct repair, and strategies for muscle regeneration.- 20 Cardiomyocytes can induce rhythmic contraction of skeletal muscle cells. Potential use for infarct repair.- 21 Strategies to identify cardiomyocyte cell cycle regulatory genes.
Erscheint lt. Verlag | 14.10.2012 |
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Zusatzinfo | X, 357 p. |
Verlagsort | Heidelberg |
Sprache | englisch |
Maße | 155 x 235 mm |
Gewicht | 569 g |
Themenwelt | Medizinische Fachgebiete ► Innere Medizin ► Kardiologie / Angiologie |
Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
Schlagworte | Arrhythmia • cardiac function • gene therapy • heart • Heart Failure • molecular approaches to heart failure • myocardial gene transfer techniques • Myocardial Infarction • pathophysiology in heart failure • Physiology • Protein • Regulation • Transplantation |
ISBN-10 | 3-642-63332-3 / 3642633323 |
ISBN-13 | 978-3-642-63332-4 / 9783642633324 |
Zustand | Neuware |
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