Diabetes and Kidney Disease (eBook)

Gunter Wolf is Professor and Chairman, Department for Internal Medicine III (Nephrology, Rheumatology, Osteology, Endocrinology and Diabetology) at the Friedrich Schiller University in Jena, Germany. Professor Wolf is well known both in Europe and America, and is involved in many editorial boards and journals such as Kidney International, Journal American Society of Nephrology, European Journal of Clinical Investigation, Hypertension and the renal section of the American Journal of Physiology. Professor Wolf is also the author of Obesity and the Kidney, Karger, 2006.

Contributors, vii

Preface, x

Part I Introduction and Pathophysiology

1 History of diabetic nephropathy: a personal account, 3

Eberhard Ritz

2 Epidemiology of chronic kidney disease in diabetes, 14

Andrea Icks and Michael Koch

3 Genetic risk factors for diabetic nephropathy, 29

Carsten A. Böger and Peter R. Mertens

4 Pathophysiology of diabetic nephropathy, 45

Ivonne Loeffler

5 Histology of human diabetic nephropathy, 62

Kerstin Amann and Christoph Daniel

6 Natural history and diagnosis of diabetic kidney disease,
70

Bethany Karl and Kumar Sharma

Part II Special Situations, Risk Factors and
Complications

7 Cardiovascular disease in diabetic nephropathy:
pathophysiology and treatment, 85

Martin Busch

8 Statin therapy in patients with diabetic nephropathy,
101

Christoph Wanner

9 Diabetes mellitus, bone and kidney, 116

Thomas Neumann and Gabriele Lehmann

10 Diabetes, pregnancy and the kidney, 129

Helmut Kleinwechter and Ute Schäfer-Graf

11 Diabetic nephropathy in children, 143

Kai D Nüsken and Jörg Dötsch

12 Diabetes, the kidney and retinopathy, 153

Hans-Peter Hammes

Part III Prevention and Therapy

13 Reducing progression of diabetic nephropathy by
antihyperglycemic treatment, 171

Christoph Hasslacher

14 Dosage of antihyperglycemic drugs in patients with renal
insuffi ciency, 186

Alexander Sämann and Ulrich A. Müller

15 Reducing progression of diabetic nephropathy by
antihypertensive treatment, 202

Anita Hansen, Ivo Quack and Lars Christian Rump

16 Treatment of the patient with end-stage diabetic nephropathy,
215

Muriel Ghosn and Fuad N. Ziyadeh

17 Combined pancreas and kidney transplantation or kidney alone
transplantation for patients with diabetic nephropathy, 232

Hermann J. Kissler, Christiane Rüster and Utz
Settmacher

Index, 253

Color plate section can be found facing

page 54

"It should therefore be essential reading for
diabetes/endocrine and renal speciality trainees. It will
also appeal to both the general practitioner and those looking
after acutely ill patients." (Diabetes Update, 1
July 2013)