Clinical Radiation Oncology

William Small Jr, MD, Professor of Radiation Oncology, Professor and Chair of the Department of Radiation Oncology, Loyola University Chicago Stritch School of Medicine, Chicago, IL, USA

Nancy J. Tarbell, MD, Dean for Academic and Clinical Affairs and the C.C. Wang Professor of Radiation Oncology, Harvard Medical School, MA, USA

Min Yao, MD, PhD, Department of Radiation Oncology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH, USA

Dr Chiu-Chen Wang, Founding Editor of ClinicalRadiation Oncology; Edited for two successful editions (1988 and 2000) by the eminent physician Dr Chiu-Chen Wang, this book was designed to offer highly practical, application-based comprehensive overview of the biological basis of radiation oncology and the clinical efficacy of radiation therapy. Dr Wang, widely known as "C.C." and well known for his "skilled and no-nonsense methods of dealing with the various types of major organ cancers," passed away in 2005. He was a highly acclaimed leader in the field of radiation oncology based at Harvard Medical School, which established the "C.C. Wang Professorship in Radiation Oncology."

Dedication ix
Preface xi
Contributors xiii
Section 1 Scientific Foundations 1 Section Editor:William Small Jr.
1 Basic Concepts of Clinical Radiation Oncology 3 Hannah Yoon, Karan Shah,William Small Jr,Minesh P.Mehta and John P. Hayes
2 Radiation Biology for Radiation Oncologists 15 Timothy A. Chan, Boris Hristov and Simon N. Powell
3 Treatment Planning 62 George T.Y. Chen and Jong H. Kung
4 Image-Guided Radiation Therapy 83 Monique Youl, Kristy K. Brock and Laura A. Dawson
5 A Guide to Understanding Statistics in Radiation Oncology 99 Kathryn Winter
6 Use of Protons for Radiation Therapy 115 Mark Pankuch, Nasiruddin Mohammed, Draik Hecksel, Steve Laub, Sean Boyer and William F. Hartsell
7 Principles of Palliative Radiation Therapy 141 Randy L. Wei, Bo A. Wan, Edward Chowand Stephen Lutz
8 Patient Safety and Quality: Management for the Radiation Oncologist 158 Fiori Alite and Abhishek A. Solanki

Section 2 Cancers of the Head and Neck 175 Section Editor: Min Yao
9 Carcinoma of the Oral Cavity 177 Keith Unger, Felix Ho, James Melotek and Nancy Lee
10 Oropharyngeal Cancer 202 Charles Woods, Mitchell Machtay and Min Yao
11 Larynx and Hypopharynx 227 Changhu Chen
12 Carcinoma of the Nasopharynx 248 Keith Unger, Felix Ho, James Melotek and Nancy Lee
13 Carcinoma of the Paranasal Sinuses and Nasal Cavity 269 Farzan Siddiqui, Nicholas Galanopoulos and Min Yao
14 Salivary Gland Carcinomas 288 Allen M. Chen
15 Cervical Nodes with Unknown Primary Carcinomas 300 Min Yao, Pierre Lavertu and Mitchell Machtay
16 Temporal Bone Tumors 313 Allen M. Chen
17 Thyroid Cancer 318 Roi Dagan and Robert J. Amdur
18 Head and Neck Radiation Therapy Sequelae and Late Complications and the Role of IMRT 335 Xiaoshen Wang and Avraham Eisbruch

Section 3 Cancer of the Intrathorax 349 Section Editor: Minesh P. Mehta
19 Lung Cancer 351 Deepak Khuntia, Pranshu Mohindra and Minesh P. Mehta
20 Carcinoma of the Esophagus 385 Grace J. Kim and Mohan Suntharalingam

Section 4 Gastrointestinal Malignancies 397 Section Editor: Christopher G.Willett
21 Gastric Cancer 399 Joanna Y. Chin and Theodore S. Hong
22 Pancreatic Cancer 409 Manisha Palta, Christopher G.Willett and Brian G. Czito
23 Colon Cancer 429 Jennifer Y. Wo
24 Rectal Cancer 438 Jennifer Y. Wo
25 Anal Cancer 466 Brian G. Czito, Manisha Palta and Christopher G. Willett

Section 5 Genitourinary Malignancies 481 Section Editor: Jason A. Efstathiou
26 Bladder Cancer 483 Phillip J. Gray,William U. Shipley and Jason A. Efstathiou
27 Prostate Cancer 497 Abhishek A. Solanki, Rebecca I. Hartman, Phillip J. Gray, Brent S. Rose, Jonathan J. Paly, Kent W. Mouw and Jason A. Efstathiou
28 Carcinoma of the Upper Urinary Tract 531 Anthony L. Zietman, Jonathan J. Paly and Jason A. Efstathiou
29 Testicular Cancer 539 Jonathan J. Paly and Jason A. Efstathiou
30 Penile Cancer 549 Kent W. Mouw, Anthony L. Zietman and Jason A. Efstathiou

Section 6 Gynecological Malignancies 557 Section Editor:William Small Jr.
31 Endometrium 559 Ann Klopp and Patricia Eifel
32 Vulva 576 Kanokpis Townamchai, Caitlin Newhouse and Akila N. Viswanathan
33 Ovary 597 Charles A. Kunos
34 Vagina 618 Charles A. Kunos
35 Cervix 631 Charles A. Kunos

Section 7 Miscellaneous Sites 673 Section Editor:William Small, Jr
36 Cancer of the Skin 675 Justin Lee, Elizabeth Barnes, May Tsao and Phillip Devlin
37 Cancer of the Breast 694 Jonathan B. Strauss, Monica Morrow and William Small Jr
38 Soft-Tissue Sarcomas 739 Jonathan B. Ashman and Kaled M. Alektiar
39 Tumors of the Central Nervous System 757 Phillip J. Gray, Jay S. Loeffler and Helen A. Shih
40 The Lymphomas 775 Caitlin Costello, Loren K. Mell and Parag Sanghvi
41 Pediatric Tumors 805 Shannon M. MacDonald, Torunn I. Yock, Nancy J. Tarbell and Tamara Z. Vern-Gross
Index 845