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The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging 2e

Software / Digital Media
512 Seiten
2013
John Wiley & Sons Inc (Hersteller)
978-1-118-50365-2 (ISBN)
195,52 inkl. MwSt
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Magnetic Resonance Imaging (MRI) is one of the most important tools in clinical diagnostics and biomedical research. This completely revised and extended second edition is presented in color and includes new chapters on targeted, responsive, PARACEST and nanoparticle MRI contrast agents. It covers the basic chemistries, MR physics and most important techniques used by chemists in the characterization of MRI agents from every angle, from synthesis to safety considerations. Essential reading for professionals involved in the development and application of contrast agents in MRI.

Lothar Helm studied physics at the University of Karlsruhe and got his diploma in 1977 in physical chemistry and electrochemistry. In 1980 he obtained his Ph.D. and joined the Institute of Inorganic Chemistry at the University of Lausanne as post-doc. In 1999 he was appointed Privat Docent at the Faculty of Science of the University of Lausanne. Since 2006 he is titular professor and director of the NMR service of the Institute of Chemical Sciences and Engineering. Andre E. Merbach, studied at the University of Lausanne and in 1964 was awarded a PhD. He then spent a Postdoctoral Fellowship in the Lawrence Radiation Laboratory at UC Berkeley. In 1965 he returned to the Institute of Inorganic and Analytical Chemistry at Lausanne and created a research and teaching program in coordination chemistry. In 1973, the Swiss Chemical Society awarded him the Werner Prize and Medal for his research and he was nominated Professor of Inorganic and Analytical Chemistry. eva T?th of the Centre de Biophysique Moleculaire, CNRS, Orleans, France, received her Ph.D. in 1994 at the University of Debrecen, Germany and then from 1995-2000 carried out post-doctoral research at the University of Lausanne with Professor Merbach. From 2001-2005 she was based at the EPFL before taking up the position of Director of Research at the CBM in Orleans. She has over 80 journal papers, 4 book chapters as well as acting as co-editor for the 1st edition of this book which was published in 2001.

List of Contributors Preface 1 GENERAL PRINCIPLES OF MRI 2 RELAXIVITY OF GADOLINIUM(III) COMPLEXES: THEORY AND MECHANISM 3 SYNTHESIS AND CHARACTERIZATION OF LIGANDS AND THEIR GADOLINIUM(III) COMPLEXES 4 STABILITY AND TOXICITY OF CONTRAST AGENTS 5 STRUCTURE, DYNAMICS AND COMPUTATIONAL STUDIES OF LANTHANIDE BASED CONTRAST AGENTS 6 ELECTRONIC SPIN RELAXATION AND OUTER-SPHERE DYNAMICS OF GADOLINIUM-BASED CONTRAST AGENTS 7 TARGETED MRI CONTRAST AGENTS 8 RESPONSIVE PROBES 9 PARAMAGNETIC CEST MRI CONTRAST AGENTS 10 Superparamagnetic Iron Oxide Nanoparticles for MRI 11 GD-CONTAINING NANOPARTICLES AS MRI CONTRAST AGENTS Subject Index

Verlagsort New York
Sprache englisch
Maße 150 x 250 mm
Gewicht 666 g
Themenwelt Medizinische Fachgebiete Radiologie / Bildgebende Verfahren Kernspintomographie (MRT)
Naturwissenschaften Chemie Analytische Chemie
Technik Umwelttechnik / Biotechnologie
ISBN-10 1-118-50365-1 / 1118503651
ISBN-13 978-1-118-50365-2 / 9781118503652
Zustand Neuware
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