The Comprehensive Sourcebook of Bacterial Protein Toxins 4th Edition, contains chapters written by internationally known and well-respected specialists. This book contains chapters devoted to individual toxins, as well as chapters that consider the different applications of these toxins. Considerable progress has been made in understanding the structure, function, interaction and trafficking into cells, as well as mechanism of action of toxins. Bacterial toxins are involved in the pathogenesis of many bacteria, some of which are responsible for severe diseases in human and animals, but can also be used as tools in cell biology to dissect cellular processes or used as therapeutic agents. Novel recombinant toxins are already proposed in the treatment of some diseases, as well as new vaccines. Alternatively, certain toxins are also considered as biological weapons or bioterrorism threats. Given the multifaceted aspects of toxin research and the multidisciplinary approaches adopted, toxins are of great interest in many scientific areas from microbiology, virology, cell biology to biochemistry and protein structure. This new edition is written with a multidisciplinary audience in mind and contains 5 new chapters that reflect the latest research in this area. Other chapters have been combined, deleted and fully revised as necessary to deliver relevant and valuable content.
- Descriptions of relevant toxins as well as representative toxins of the main bacterial toxin families to allow for a better comparison between them.
- Focused chapters on toxin applications and common properties or general features of toxins.
Joseph E. Alouf is Professor of Microbiology at the Pasteur Institute of Lille. He is former Head of the Department of Bacteriology and Mycology at the Pasteur Institute at Paris and Chairman of its Scientific Council. He served as Secretary General of the French Society of Immunology from 1984-1986 and President of the Federation of the European Microbiological Societies from 1989-1992. His 40-year research work relates to the field of bacterial protein toxins and immunology of infectious diseases. He is also the co-editor of several books.
The Comprehensive Sourcebook of Bacterial Protein Toxins, Fourth Edition, contains chapters written by internationally known and well-respected specialists. This book contains chapters devoted to individual toxins, as well as chapters that consider the different applications of these toxins. Considerable progress has been made in understanding the structure, function, interaction and trafficking into cells, as well as mechanism of action of toxins. Bacterial toxins are involved in the pathogenesis of many bacteria, some of which are responsible for severe diseases in human and animals, but can also be used as tools in cell biology to dissect cellular processes or used as therapeutic agents. Novel recombinant toxins are already proposed in the treatment of some diseases, as well as new vaccines. Alternatively, certain toxins are also considered as biological weapons or bioterrorism threats. Given the multifaceted aspects of toxin research and the multidisciplinary approaches adopted, toxins are of great interest in many scientific areas from microbiology, virology, cell biology to biochemistry and protein structure. This new edition is written with a multidisciplinary audience in mind and contains 5 new chapters that reflect the latest research in this area. Other chapters have been combined, deleted and fully revised as necessary to deliver relevant and valuable content. Descriptions of relevant toxins as well as representative toxins of the main bacterial toxin families to allow for a better comparison between them Focused chapters on toxin applications and common properties or general features of toxins
List of Contributors
Klaus Aktories, Institut für Experimentelle und Klinische Pharmakologie und Toxikologie der Universität Freiburg, Freiburg, Germany
Alberto Alape-Girón, Instituto Clodomiro Picado, Facultad de Microbiología; Departamento de Bioquímica, Escuela de Medicina Universidad de Costa Rica, San José, Costa Rica
Julien Barbier, Institute of Biology and Technology of Saclay, Gif sur Yvette, France
Joseph T. Barbieri, Professor Microbiology and Molecular Genetics Medical College of Wisconsin, Milwaukee, WI, USA
Holger Barth, Institute of Pharmacology and Toxicology, University of Ulm Medical Center, Ulm, Germany
Ajit K. Basak, Department of Biological Sciences, School of Crystallography, Birkbeck College, Malet Street, London, UK
Roland Benz, Department of Life Science and Chemistry, Jacobs University Bremen, Bremen, Germany
Kinga Bercsenyi
Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, University College London, London, UK
Molecular NeuroPathobiology Laboratory, Cancer Research UK London Research Institute, London, UK
Jonas Bergan
Centre for Cancer Biomedicine, Faculty of Medicine, University of Oslo, Oslo, Norway
Department of Biochemistry, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway
Stefan Bergmann, Institut für Experimentelle und Klinische Pharmakologie und Toxikologie, Albert-Ludwigs-Universität Freiburg, Freiburg, Germany
Sergey M. Bezrukov, Program in Physical Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
Victoria A. Bjørnestad, Department of Chemistry, University of Oslo, Oslo, Norway
Patrice Boquet, Nice University School of Medicine, Nice, France
Laurent Boyer, INSERM, U1065, C3M, Université de Nice Sophia-Antipolis, Equipe Labellisée Ligue Contre le Cancer, Nice, France
Alejandra Bravo, Instituto de Biotecnologia, Universidad Nacional Autónoma de México, Cuernavaca Morelos, Mexico
Amy E. Bryant
Infectious Diseases Section, Veterans Affairs Medical Center, Boise, ID, USA
University of Washington School of Medicine, Seattle, WA, USA
Ladislav Bumba, Laboratory of Molecular Biology of Bacterial Pathogens, Cell and Molecular Microbiology Division, Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic
Pablo Emiliano Cantón, Instituto de Biotecnologia, Universidad Nacional Autónoma de México, Cuernavaca Morelos, Mexico
Alexandre Chenal, Institut Pasteur, CNRS UMR 3528, Unité de Biochimie des Interactions Macromoléculaires, Département de Biologie Structurale et Chimie, Paris, France
Matteo Dal Peraro
Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland
Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland
Marcela de Souza Santos, Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA
Ulrich Dobrindt, Institute of Hygiene, University of Münster, Münster, Germany
J. Oliver Dolly, International Centre for Neurotherapeutics, Dublin City University, Dublin, Ireland
J. Daniel Dubreuil, Department of Pathology and Microbiology, Université de Montréal, Québec, Canada
Alain Filloux, MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College London, London, UK
Dara W. Frank, Professor Microbiology and Molecular Genetics Medical College of Wisconsin, Milwaukee, WI, USA
Marietta Flores-Díaz, Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica
John D. Fraser, School of Medical Sciences, University of Auckland and Maurice Wilkins Centre, Auckland, New Zealand
Teresa Frisan, Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden
Jorge E. Galan, Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA
Blanca I. García-Gómez, Instituto de Biotecnologia, Universidad Nacional Autónoma de México, Cuernavaca Morelos, Mexico
Harald Genth, Institute of Toxicology, Hannover Medical School, Hannover, Germany
Daniel Gillet, Institute of Biology and Technology of Saclay, Gif sur Yvette, France
Isabel Gómez, Instituto de Biotecnologia, Universidad Nacional Autónoma de México, Cuernavaca Morelos, Mexico
Per Einar Granum, Norwegian University of Life Sciences, NMBU—School of Veterinary Science, Department of Food Safety and Infection Biology, Oslo, Norway
Jörg Hacker, National German Academy of Sciences Leopoldina, Halle/Saale, Germany
Callista B. Harper, University of Queensland, Queensland Brain Institute, Clem Jones Centre for Ageing Dementia Research, Brisbane, Australia
Julie E. Heggelund, Department of Chemistry, University of Oslo, Oslo, Norway
Mengfei Ho, Department of Microbiology, School of Molecular and Cellular Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA
Eileen M. Hotze, Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA
Jessica Huyet, Department of Biological Sciences, School of Crystallography, Birkbeck College, Malet Street, London, UK
Ioan Iacovache, Laboratory of Experimental Morphology, Institute of Anatomy, University of Bern, Bern, Switzerland
Thomas Jank, Institut für Experimentelle und Klinische Pharmakologie und Toxikologie der Universität Freiburg, Freiburg, Germany
Emmanuel Jover, EA-7290 Virulence bactérienne précoce, Fédération de Médecine Translationnelle, Université de Strasbourg, Institut de Bactériologie, Strasbourg, France
Ingo Just, Institute of Toxicology, Hannover Medical School, Hannover, Germany
Anne-Marie Krachler, Institute of Microbiology and Infection, University of Birmingham, UK
Ute Krengel, Department of Chemistry, University of Oslo, Oslo, Norway
Daniel Ladant, Institut Pasteur, CNRS UMR 3528, Unité de Biochimie des Interactions Macromoléculaires, Département de Biologie Structurale et Chimie, Paris, France
Ries J. Langley, School of Medical Sciences, University of Auckland and Maurice Wilkins Centre, Auckland, New Zealand
Emmanuel Lemichez, INSERM, U1065, C3M, Université de Nice Sophia-Antipolis, Equipe Labellisée Ligue Contre le Cancer, Nice, France
Stephen...
| Erscheint lt. Verlag | 29.5.2015 |
|---|---|
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Gesundheitsfachberufe |
| Studium ► 2. Studienabschnitt (Klinik) ► Pharmakologie / Toxikologie | |
| Naturwissenschaften ► Biologie ► Biochemie | |
| Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie | |
| Naturwissenschaften ► Biologie ► Ökologie / Naturschutz | |
| Naturwissenschaften ► Physik / Astronomie ► Angewandte Physik | |
| Technik | |
| ISBN-10 | 0-12-800589-0 / 0128005890 |
| ISBN-13 | 978-0-12-800589-7 / 9780128005897 |
| Haben Sie eine Frage zum Produkt? |
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