Water Soluble Vitamins
Today, it is not the previously fatal deficiency-associated diseases that are in the focus of interest, but rather the relation of suboptimal vitamin bioavailability to chronic disease. This is complicated by genetic susceptibility, lifestyle, and the presence or absence of health-compromising habits, such as smoking. In turn, the development and application of new and more sensitive and specific assays further enable us to look more closely into the many functions of vitamins.
Water soluble vitamins are complex molecular structures and even today, many areas in vitamin biochemistry are not yet fully understood. Novel effects and functions of vitamins remain and continue to be discovered. This book presents most recent research results and fascinating new knowledge on the role and effects of the water soluble vitamins in man. Some of the most distinguished chemists, biochemists, biologists and clinicians have contributed valuable chapters sharing unexpected novel insights into the biochemistry, (epi)genetics, metabolism, and function of water soluble vitamins, withtheir potential for clinical applications.
Thus, physicians, clinicians, scientists, researchers, epidemiologists. nutritional specialists and health professionals alike will find stimulating and fascinating new insight in the many roles that water soluble vitamins play in human health and disease.
Preface.- 1. Biotin: Biochemical, Physiological and Clinical Aspects.- 2. Niacin status and genomic instability in bone marrow cells; Mechanisms favoring the progression of leukemogenesis.- 3. Niacin: Vitamin and Antidyslipidemic Drug.- 4. Beyond the antioxidant: the double life of vitamin C.- 5. Vitamin C in Sepsis.- 6. Vitamin C transport and its role in the central nervous system.- 7. Genetic aspects of folate metabolism.- 8. Enzymatic and non-enzymatic antioxidative effects of folic acid and its reduced derivates.- 9. Folate-linked drugs for the treatment of cancer and inflammatory diseases.- 10. Folate in Skin Cancer Prevention.- 11. Thiamin(E): The spark of life.- 12. Riboflavin in development and cell fate.- 13. Vitamins B6 and Cancer.- 14. Vitamin B6 and cardiovascular disease.- 15.- Vitamin B6: Beyond coenzyme functions.- 16.- Cobalamin Deficiency.- 17. Biochemistry of B12-Cofactors in Human Metabolism.- 18. Physiological and molecular aspects of cobalamin transport.- Index.
Reihe/Serie | Subcellular Biochemistry ; 56 |
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Zusatzinfo | XVI, 384 p. |
Verlagsort | Dordrecht |
Sprache | englisch |
Maße | 155 x 235 mm |
Themenwelt | Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie |
Naturwissenschaften ► Biologie ► Biochemie | |
Naturwissenschaften ► Biologie ► Zellbiologie | |
ISBN-10 | 94-007-2198-6 / 9400721986 |
ISBN-13 | 978-94-007-2198-2 / 9789400721982 |
Zustand | Neuware |
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