Industrial Scale Suspension Culture of Living Cells (eBook)
642 Seiten
Wiley-VCH (Verlag)
978-3-527-68335-2 (ISBN)
All chapters adhere to a standardized structure and the editors have carefully avoided any overlaps in content. The following are included for each host or expression system presented:
(a) organisms, cells, expression systems, products,
(b) basic process design aspects,
(c) basic bioreactor design aspects,
(d) key factors affecting process economics,
(e) regulatory aspects,
(f) summary and outlook.
The holder of a PhD in microbiology from the University of Fribourg, Switzerland, Hans-Peter Meyer served as VP Strategic Projects Biotechnology at Lonza until his retirement in early 2014. Following three years of postdoctoral studies in Stockholm, at the University of Pennsylvania, Philadelphia, and Lehigh University, Bethlehem, USA, in 1982 he joined Prof. Armin Fiechter's team as group leader at the ETH in Zürich before starting at Lonza in Visp, Switzerland in 1986, where he held a number of positions in R&D, manufacturing, and sales & marketing. He recently joined the faculty of the University of Applied Sciences and Arts of Western Switzerland, and also remains an expert at the Commission for Technology & Innovation (CTI) of the Swiss Federal Confederation. Diego R. Schmidhalter is head of R&T within the pharma and biotechnology custom manufacturing division at Lonza Switzerland. He holds a PhD in microbiology from the University of Fribourg, Switzerland, and carried out two years of postdoctoral studies at Genencor International, California, USA. He has held various management positions at Lonza, including head of microbial anufacturing, head of the Biopharma R&D Services business, and as head of Microbial Manufacturing Science and Technology, as well as being a member of the Biopharmaceuticals business team. Dr. Schmidhalter has over 20 years of experience in the biotechnology industry in biopharmaceuticals and biochemicals process development and manufacturing, technology transfer, scaling-up fermentations right up to the 50,000-liter scale, and within the biopharmaceuticals related regulatory environment.
The History and Economic Relevance of Industrial Scale Suspension Culture of Living Cells (Hans-Peter Meyer, Diego R. Schmidhalter)
PART I: SUSPENSION CULTURE OF BACTERIA, YEASTS, AND FILAMENTOUS FUNGI
Bacterial Suspension Cultures (Patrick Sagmeister, Mohammad Jazini, Joachim Klein, and Christoph Herwig)
Yeast Suspension Culture (Diethard Mattanovich, Carmen Jungo, Jana Wenger, Michal Dabros, and Michael Maurer)
Filamentous Fungi Fermentation (Anders Norregaard, Stuart M. Stocks, Mads O. Albaek, John M. Woodley, and Krist V. Gernaey)
PART II: SUSPENSION CULTURE OF ALGAE AND PLANT CELLS
Microalgae Grown Under Heterotrophic and Mixotrophic Conditions (Karin Kovar, Pavel Pribyl, and Markus Wyss)
Recombinant Protein Production with Microalgae (Alexandre Lejeune, Rémy Michel, and Aude Carlier)
Suspension Culture of Microorganisms (Algae and Cyanobacteria)under Phototrophic Conditions (Peter Bergmann, Astrid Nissen, Lars Beyer, Peter Ripplinger, Walter Trösch)
Suspension Culture of Plant Cells under Heterotrophic Conditions (Nicole Imseng, Stefan Schillberg, Cornelia Schürch, Daniel Schmid, Kai Schütte, Gilbert Gorr, Dieter Eibl, and Regine Eibl)
Suspension Culture of Plant Cells under Phototrophic Conditions (Holger Niederkrüger, Paulina Dabrowska-Schlepp, and Andreas Schaaf)
PART III: SUSPENSION CULTURE OF PROTOZOA, INSECT CELLS, AVIAN CELLS, AND MAMMALIAN CELLS
Suspension Culture of Protozoan Organisms (M.W.W. Hartmann and R. Breitling)
Industrial Large Scale of Suspension Culture of Insect Cells (António Roldão, Manon Cox, Paula Alves, Manuel Carrondo, and Tiago Vicente)
Avian Suspension Culture Cell Lines for Production of Vaccines and Other Biologicals (Manfred Reiter, Daniel Portsmouth, and P. Noel Barrett)
Large Scale Suspension Culture of Mammalian Cells (Richard M Alldread, John R. Birch, Hilary K Metcalfe, Suzanne Farid, Andrew J. Racher, Robert J. Young, and Mohsan Khan)
PART IV: SUSPENSION CULTURE FOR SPECIAL PRODUCTS
Pillars of Regenerative Medicine: Therapeutic Human Cells and Their Manufacture
(Christian van den Bos, Robert Keefe, Carmen Schirmaier, and Michael McCaman)
Virus Production Under Suspension Conditions (O.-W. Merten, W.A.M. Bakker, J. Vorlop, M. Reiter, G. Visnovsky, V. Jäger, M. Merabishvili, and U. Reichl)
Cultivable Marine Organisms as a Source of New Products (Jean-Michel Kornprobst)
Erscheint lt. Verlag | 30.7.2014 |
---|---|
Sprache | englisch |
Themenwelt | Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie |
Technik | |
Schlagworte | Biotechnologie • Biotechnologie i. d. Biowissenschaften • Biotechnologie i. d. Chemie • Biotechnology • Biowissenschaften • Chemie • Chemistry • Industrial Engineering • Industrial Engineering Special Topics • Industrielle Biotechnologie • Industrielle Verfahrenstechnik • Life Sciences • Spezialthemen Industrielle Verfahrenstechnik • Verfahrenstechnik |
ISBN-10 | 3-527-68335-6 / 3527683356 |
ISBN-13 | 978-3-527-68335-2 / 9783527683352 |
Haben Sie eine Frage zum Produkt? |
Größe: 9,6 MB
Kopierschutz: Adobe-DRM
Adobe-DRM ist ein Kopierschutz, der das eBook vor Mißbrauch schützen soll. Dabei wird das eBook bereits beim Download auf Ihre persönliche Adobe-ID autorisiert. Lesen können Sie das eBook dann nur auf den Geräten, welche ebenfalls auf Ihre Adobe-ID registriert sind.
Details zum Adobe-DRM
Dateiformat: EPUB (Electronic Publication)
EPUB ist ein offener Standard für eBooks und eignet sich besonders zur Darstellung von Belletristik und Sachbüchern. Der Fließtext wird dynamisch an die Display- und Schriftgröße angepasst. Auch für mobile Lesegeräte ist EPUB daher gut geeignet.
Systemvoraussetzungen:
PC/Mac: Mit einem PC oder Mac können Sie dieses eBook lesen. Sie benötigen eine
eReader: Dieses eBook kann mit (fast) allen eBook-Readern gelesen werden. Mit dem amazon-Kindle ist es aber nicht kompatibel.
Smartphone/Tablet: Egal ob Apple oder Android, dieses eBook können Sie lesen. Sie benötigen eine
Geräteliste und zusätzliche Hinweise
Buying eBooks from abroad
For tax law reasons we can sell eBooks just within Germany and Switzerland. Regrettably we cannot fulfill eBook-orders from other countries.
aus dem Bereich