Clinical Virology Manual

Contributors
Author Biographies
Preface to the Fifth Edition
SECTION I
GENERAL TOPICS IN CLINICAL VIROLOGY
1 The Taxonomy, Classification, and Characterization of Medically Important Viruses / 3
STEVEN J. DREWS
2 Quality Assurance and Quality Control in Clinical and Molecular Virology / 27
MATTHEW J. BANKOWSKI
3 Regulatory Compliance / 35
LINOJ SAMUEL
4 Laboratory Safety / 41
K. SUE KEHL
5 Laboratory Design / 51
MATTHEW J. BINNICKER
SECTION II
LABORATORY PROCEDURES FOR DETECTING VIRUSES
6 Specimen Requirements Selection, Collection, Transport, and Processing / 59
REETI KHARE AND THOMAS E. GRYS
7 Primary Isolation of Viruses / 79
MARIE L. LANDRY AND DIANE LELAND
8 Viral Antigen Detection / 95
DIANE S. LELAND AND RYAN F. RELICH
9 Serologic (Antibody Detection)
Methods / 105
DONGXIANG XIA, DEBRA A. WADFORD,
CHRISTOPHER P. PREAS, AND DAVID P. SCHNURR
10 Nucleic Acid Extraction in Diagnostic Virology / 117
RAYMOND H. WIDEN AND SUZANE SILBERT
11 Nucleic Acid Amplification by Polymerase Chain Reaction / 129
ANA MARIA CARDENAS AND KEVIN ALBY
12 Isothermal Nucleic Acid Amplification Methods / 137
HARALD H. KESSLER AND EVELYN STELZL
13 Quantitative Molecular Methods / 145
NATALIE N. WHITFIELD AND DONNA M. WOLK
14 Signal Amplification Methods / 167
YUN (WAYNE) WANG
15 DNA Sequencing for Clinical and Public Health Virology: Some Assembly Required / 173
JOANNE BARTKUS
16 Phenotypic and Genotypic Antiviral Susceptibility Testing / 201
MARTHA T. VAN DER BEEK AND ERIC C. J. CLAAS
17 Point-of-Care Diagnostic Virology / 229
JAMES J. DUNN AND LAKSHMI CHANDRAMOHAN
18 Future Technology / 243
ERIN MCELVANIA TEKIPPE AND CAREY-ANN D. BURNHAM
SECTION III
VIRAL PATHOGENS
19 Respiratory Viruses / 257
CHRISTINE ROBINSON, MICHAEL J. LOEFFELHOLZ,
AND BENJAMIN A. PINSKY
20 Enteroviruses and Parechoviruses / 277
M. STEVEN OBERSTE AND MARK A. PALLANSCH
21 Measles, Mumps, and Rubella Viruses / 293
WILLIAM J. BELLINI, JOSEPH P. ICENOGLE, AND CAROLE J. HICKMAN
22 Gastrointestinal Viruses / 311
MICHAEL D. BOWEN
23 Hepatitis A and E Viruses / 329
GILBERTO VAUGHAN AND MICHAEL A. PURDY
24 Hepatitis B and D Viruses / 341
REBECCA T. HORVAT
25 Hepatitis C Virus / 351
MELANIE MALLORY AND DAVID HILLYARD
26 Herpes Simplex Viruses and Varicella Zoster Virus / 363
SCOTT H. JAMES AND MARK N. PRICHARD
27 Cytomegalovirus / 373
PREETI PANCHOLI AND STANLEY I. MARTIN
28 Epstein-Barr Virus / 387
DERRICK CHEN AND BELINDA YEN-LIEBERMAN
29 Human Herpesviruses 6, 7, and 8 / 399
SHEILA C. DOLLARD AND TIMOTHY M. KARNAUCHOW
30 Human Papillomaviruses / 413
SUSAN NOVAK-WEEKLEY AND ROBERT PRETORIUS
31 Human Polyomaviruses / 427
REBECCA J. ROCKETT, MICHAEL D. NISSEN, THEO
P. SLOOTS, AND SEWERYN BIALASIEWICZ
32 Parvoviruses / 443
RICHARD S. BULLER
33 Poxviruses / 457
ASHLEY V. KONDAS AND VICTORIA A. OLSON
34 Rabies Virus / 473
ROBERT J. RUDD AND APRIL D. DAVIS
35 Arboviruses / 493
LAURA D. KRAMER, ELIZABETH B. KAUFFMAN,
NORMA P. TAVAKOLI
36 Animal-Borne Viruses / 515
GREGORY J. BERRY, MICHAEL J. LOEFFELHOLZ, AND GUSTAVO PALACIOS
37 Human Immunodeficiency Viruses and
Human T-lymphotropic Viruses / 527
JOERG SCHUEPBACH
38 Chlamydiae / 545
BARBARAVAN DER POL AND CHARLOTTE A. GAYDOS
39 The Human Virome / 561
MATTHEW C. ROSS, NADIM J. AJAMI, AND JOSEPH F. PETROSINO
40 Human Susceptibility and Response
to Viral Diseases / 567
VILLE PELTOLA AND JORMA ILONEN
APPENDIXES: REFERENCE VIROLOGY
LABORATORIES
APPENDIX 1 Reference Virology Laboratory
Testing Performed at the Centers for Disease Control / 581
ROBERTA B. CAREY
APPENDIX 2 Public Health Laboratory Virology Services / 585
JANE GETCHELL
APPENDIX 3 International Reference Laboratories Offering Virology Services / 595
ARIEL I. SUAREZ AND CRISTINA VIDELA
INDEX / 607