Diffusion Tensor Imaging (eBook)

A Practical Handbook
eBook Download: PDF
2015 | 1st ed. 2016
XVIII, 440 Seiten
Springer New York (Verlag)
978-1-4939-3118-7 (ISBN)

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This book provides an overview of the practical aspects of diffusion tensor imaging (DTI), from understanding the basis of the technique through selection of the right protocols, trouble-shooting data quality, and analyzing DTI data optimally. DTI is a non-invasive magnetic resonance imaging (MRI) technique for visualizing and quantifying tissue microstructure based on diffusion. The book discusses the theoretical background underlying DTI and advanced techniques based on higher-order models and multi-shell diffusion imaging. It covers the practical implementation of DTI; derivation of information from DTI data; and a range of clinical applications, including neurosurgical planning and the assessment of brain tumors. Its practical utility is enhanced by decision schemes and a fully annotated DTI brain atlas, including color fractional anisotropy maps and 3D tractography reconstructions of major white matter fiber bundles. Featuring contributions from leading specialists in the field of DTI, Diffusion Tensor Imaging: A Practical Handbook is a valuable resource for radiologists, neuroradiologists, MRI technicians and clinicians.

Wim Van Hecke, PhD, is an international expert in MRI analysis and advanced neuroimaging techniques and applications. An academic engineer by training with two Masters degrees in applied biomedical engineering and neuroimaging, and a PhD in diffusion MRI analysis, Dr. Van Hecke presently divides his time between pursuing research in advanced DTI analysis at Antwerp University Hospital and managing the business operations of icoMetrix, a rapidly expanding medical image analysis service that he co-founded to make state-of-the-art image analysis accessible to all.
Louise Emsell, PhD, is a translational neuroimaging expert and educator. Presently based at the University Psychiatry Centre (UPC) and Translational MRI departments at the KU Leuven University Hospital in Belgium, Dr. Emsell has two Masters degrees in Science (Medical Physics/Medicinal Chemistry) and Education, and a PhD in Psychiatry. Her award-winning postdoctoral research combines many advanced neuroimaging techniques, including state-of-the-art diffusion MRI, to study the development and evolution of psychopathology.
Stefan Sunaert, MD, PhD, is a Consultant Neuroradiologist, Professor of Neuroradiology and internationally-renowned expert in all aspects of clinical and academic MR neuroimaging. Presently head of the Translational MRI Department at KU Leuven, and based in the Radiology Department of the KU Leuven University Hospital in Belgium, Professor Sunaert has published widely in the field of Neuroradiology and has received numerous awards for his academic research. Additionally, he is a highly-respected clinician and educator who has organised numerous advanced neuroimaging courses and workshops at conferences across the world.


This book provides an overview of the practical aspects of diffusion tensor imaging (DTI), from understanding the basis of the technique through selection of the right protocols, trouble-shooting data quality, and analyzing DTI data optimally. DTI is a non-invasive magnetic resonance imaging (MRI) technique for visualizing and quantifying tissue microstructure based on diffusion. The book discusses the theoretical background underlying DTI and advanced techniques based on higher-order models and multi-shell diffusion imaging. It covers the practical implementation of DTI; derivation of information from DTI data; and a range of clinical applications, including neurosurgical planning and the assessment of brain tumors. Its practical utility is enhanced by decision schemes and a fully annotated DTI brain atlas, including color fractional anisotropy maps and 3D tractography reconstructions of major white matter fiber bundles. Featuring contributions from leading specialists in the field ofDTI, Diffusion Tensor Imaging: A Practical Handbook is a valuable resource for radiologists, neuroradiologists, MRI technicians and clinicians.

Wim Van Hecke, PhD, is an international expert in MRI analysis and advanced neuroimaging techniques and applications. An academic engineer by training with two Masters degrees in applied biomedical engineering and neuroimaging, and a PhD in diffusion MRI analysis, Dr. Van Hecke presently divides his time between pursuing research in advanced DTI analysis at Antwerp University Hospital and managing the business operations of icoMetrix, a rapidly expanding medical image analysis service that he co-founded to make state-of-the-art image analysis accessible to all. Louise Emsell, PhD, is a translational neuroimaging expert and educator. Presently based at the University Psychiatry Centre (UPC) and Translational MRI departments at the KU Leuven University Hospital in Belgium, Dr. Emsell has two Masters degrees in Science (Medical Physics/Medicinal Chemistry) and Education, and a PhD in Psychiatry. Her award-winning postdoctoral research combines many advanced neuroimaging techniques, including state-of-the-art diffusion MRI, to study the development and evolution of psychopathology. Stefan Sunaert, MD, PhD, is a Consultant Neuroradiologist, Professor of Neuroradiology and internationally-renowned expert in all aspects of clinical and academic MR neuroimaging. Presently head of the Translational MRI Department at KU Leuven, and based in the Radiology Department of the KU Leuven University Hospital in Belgium, Professor Sunaert has published widely in the field of Neuroradiology and has received numerous awards for his academic research. Additionally, he is a highly-respected clinician and educator who has organised numerous advanced neuroimaging courses and workshops at conferences across the world.

Part I  Introduction Ch. 1: How to Use This Book            Louise Emsell Ch. 2: Introduction to Diffusion Tensor Imaging            Louise EmsellWim Van HeckeJacques-Donald Tournier  Part II Diffusion Tensor Imaging: From Theory to Practice  Ch. 3: Concepts of Diffusion in MRI            Matthew RoweBernard SiowDaniel C. AlexanderUran FeriziSimon Richardson Ch. 4: From Diffusion to the Diffusion TensorThijs Dhollander  Ch. 5: Quantitative DTI MeasuresKathleen M. CurranLouise EmsellAlexander Leemans Ch. 6: Survivor’s Guide to DTI AcquisitionEric PetersonRoland Bammer Ch. 7: Checking and Correcting DTI DataChantal M.W. TaxSjoerd B. VosAlexander Leemans     Part III Diffusion Tensor Imaging Analysis       Ch. 8: Strategies and Challenges in DTI AnalysisWim Van HeckeLouise Emsell Ch. 9: DTI Analysis Methods: Region of Interest AnalysisMartijn FroelingPim PullensAlexander Leemans Ch. 10: DTI Analysis Methods: Voxel-based Analysis            Wim Van HeckeAlexander LeemansLouise Emsell Ch. 11: DTI Analysis Methods: Fibre Tracking and Connectivity            Matthan W.A. Caan  Part IV Normal Diffusion Tensor Imaging Anatomy   Ch. 12: Normal Diffusion Tensor Imaging-based White Matter Anatomy            Bram Stieltjes  Part V Clinical Applications of Diffusion Tensor Imaging   Ch. 13: DTI in Clinical Practice: Opportunities and Considerations            Louise EmsellStefan Sunaert Ch. 14: DTI in Neurosurgical Planning            Ronald L. WolfPaolo G. NuciforaElias R. Melhem Ch. 15: DTI in Diagnosis and Follow-up of Brain Tumors            Frank De BelderSophie Van CauterLuc van den HauweWim Van HeckeLouise EmsellMaya De BelderMatthias SpaepenStefan SunaertPaul M. Parizel Ch. 16: The Role of DTI in Multiple Sclerosis and Other Demyelinating Conditions            Massimo FilippiElisabetta PaganiPaolo PreziosaMaria Assunta Rocca Ch. 17: DTI in Dementing Conditions            Massimo FilippiFederica AgostaEdoardo Gioele Spinelli Ch. 18: DTI in Psychiatry            Josselin HouenouLouise Emsell Ch. 19: Diffusion Tensor Imaging in Traumatic Brain Injury            Sener SüleymanPaul M. ParizelAndrew I.R. Maas             Part VI  Beyond Diffusion Tensor Imaging      Ch. 20: High Angular Resolution Diffusion Imaging            Shawna FarquharsonJacques-Donald Tournier  Ch. 21: Diffusion Kurtosis Imaging            Jelle VeraartJan Sijbers Glossary

Erscheint lt. Verlag 14.12.2015
Zusatzinfo XVIII, 440 p. 289 illus., 238 illus. in color.
Verlagsort New York
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Neurologie
Medizinische Fachgebiete Radiologie / Bildgebende Verfahren Kernspintomographie (MRT)
Medizinische Fachgebiete Radiologie / Bildgebende Verfahren Radiologie
Studium 2. Studienabschnitt (Klinik) Anamnese / Körperliche Untersuchung
Naturwissenschaften Biologie Humanbiologie
Naturwissenschaften Biologie Zoologie
Schlagworte diagnostic radiology • diffusion kurtosis imaging • Functional Imaging • high angular resolution diffusion imaging • quantitative brain imaging • tractography • voxel-based analysis
ISBN-10 1-4939-3118-0 / 1493931180
ISBN-13 978-1-4939-3118-7 / 9781493931187
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