AntiBase: The Natural Compound Identifier

Focused antimicrobial research through high-throughput screening library

Developed by Dr. Hartmut Laatsch, AntiBase: The Natural Compound Identifieris a compilation of natural products featuring properties of more than 40,000 compounds and over 41,000 chemical structures. This indispensable database provides researchers with a convenient way of checking if a compound with antimicrobial effects has already been studied and provides insights into biological activity correlated to structural information.

AntiBase includes compound property (molecular formula, mass, elemental composition, compound class), physico-chemical (melting point, optical rotation) and spectroscopic data (UV, 13C-NMR, IR, HRMS and mass spectra). Data has been collected from the primary and secondary literature, and then carefully checked and validated with most key references and source information provided as a data field.

Another unique feature of AntiBase is access to predicted 13C-NMR spectra for compounds in which no measured spectra are available. As an NMR shift search can easily be combined with a substructure search, this spectral data further enhances the power of AntiBase to easily differentiate between similar compounds. The predicted, high-quality NMR spectra were produced by Wiley's proprietary NMR spectrum prediction algorithm.

For more information, visit https://sciencesolutions.wiley.com/solutions/technique/lc-ms/antibase-the-natural-compound-identifier/