Handbook of Clinical Pediatric Endocrinology (eBook)

Dr Charles Brook MBBChir MA MD FRCP FRCPCH Former Director, London Centre for Paediatric Endocrinology and Metabolism; Professor of Paediatric Endocrinology, University College, and Consultant Paediatrician, University College London Hospitals and Great Ormond Street Children's Hospital, London Dr Brook trained at Cambridge University, UK, St Thomas's and Great Ormond Street Hospitals, London, UK and Kinderspital Zürich, Switzerland. He achieved a personal chair in Paediatric Endocrinology at University College London in 1989. In 1994, he initiated the London Centre for Paediatric Endocrinology providing a seamless service for infants, children, adolescents and adults between Great Ormond Street and University College London Hospitals. He is currently Emeritus Professor of Paediatric Endocrinology at University College London and honorary consulting paediatric endocrinologist to Great Ormond Street and University College London Hospitals. Dr Brook's main research interests are all aspects of paediatric endocrinology, particularly skeletal dysplasias, endocrine damage by radiotherapy, and Turner Syndrome. Dr. Brown is currently an Associate Professor of Pediatrics at Harvard Medical School and the Director of Clinical Trials Research in the Endocrine Division at Children's Hospital Boston. She was the founding director of the Division of Pediatric Endocrinology/Diabetes at the University of Massachusetts Medical Center where she rose to the rank of Professor of Pediatrics with tenure. She has authored more than 70 original manuscripts, reviews, editorials and book chapters and is a co-editor of the 5th edition, Brook's Clinical Pediatric Endocrinology. She has played leadership roles in education and clinical practice. She was the Chair of the Program Committee, Lawson Wilkins Pediatric Endocrine Society, a member of the National Academy of Science Committee on Toxicological Assessment of Perchlorate Ingestion and has served on the Editorial Boards of the Journal of Clinical Endocrinology & Metabolism and Thyroid She was the Editor of the Growth and Development section of Current Opinion in Endocrinology & Metabolism and is currently an Associate Editor of Endocrine Practice and a member of the American Board of Pediatrics, sub-Committee on Pediatric Endocrinology.

Handbook of Clinical Pediatric Endocrinology 5
Contents 7
Preface 9
1 The Application of Science to Clinical Practice 11
2 The Endocrine Problems of Infancy 24
3 Problems of Growth in Childhood 43
4 Problems of Puberty and Adolescence 69
5 The Thyroid Gland 94
6 The Adrenal Gland 109
7 Disorders of Calcium and Bone Metabolism 133
8 Water Balance 156
9 Polyglandular Syndromes 174
10 Hypoglycemia 182
11 Obesity and Type 2 Diabetes Mellitus 189
12 Type 1 Diabetes Mellitus 199
13 Tests and Normal Values in Pediatric Endocrinology 224
Appendix 1: Syndrome-Specific Growth Charts 248
Appendix 2: Normal Values 260
Index 267

"A practical text written by known experts covering in 12
chapters the most frequent endocrine disorders in childhood."
(Pediatric Endocrinology, May 2009)

"A well-produced book which is very useful to its target
audience ... Excellent drawings. Information is comprehensive
and well written." (BMA Medical Book Competition - Programme and
Award Winners, September 2008)