Handbook of Combinatorial Chemistry – Drugs, Catalysts, Materials

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GENERAL ASPECTS Combinatorial Chemistry in Drug Discovery Principles of Combinatorial Chemistry Solid and Soluble Supports for Heterogenous Systems Linkers for Solid Phase Synthesis Encoding Technologies Instrumentation for Combinatorial Chemistry SYNTHETIC CHEMISTRY Radical Chemistry Nucleophilic Substitution Electrophilic Substitution Elimination Addition to CC Multiple Bonds Except CC Bond Formation Addition to CX Multiple Bonds Except CO Double Bonds Chemistry of the Carbonyl Group Oxidation Except CC Double Bonds Reduction Except CC Double Bonds Cycloaddition Main Group Organometallics Enolates and Related Species Transitions Metal Catalyzed Formation of Single Bonds Metathesis and Related Processes for CC Multiple Bond Formation SPECIAL SYNTHETIC TOPICS Libraries of Natural Products Synthesis of Heterocyclic Systems Multicomponent Reactions Combinatorial Chemistry of Oligosaccharides DESIGN OF COMBINATORIAL LIBRARIES Design Criteria Estimation of Physicochemical Parameters Virtual Libraries and Modeling Case Study: Medicinal Chemistry NOVEL APPLICATIONS OF COMBINATORIAL CHEMISTRY Combinatorial Chemistry in the Fine Chemical Industry High Throughput Process Research Combinatorial Approaches to Catalyst Discovery Case Study: Combinatorial Catalyst Discovery Combinatorial Aspects of Material Research Combinatorial Principles of Biology and Their Potential Applications to Drug Discovery