Handbook of Practical Immunohistochemistry -

Handbook of Practical Immunohistochemistry (eBook)

Frequently Asked Questions
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2015 | 2nd ed. 2015
XV, 764 Seiten
Springer New York (Verlag)
978-1-4939-1578-1 (ISBN)
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171,19 inkl. MwSt
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In a conceptually current, quick-reference, Question & Answer format, the second edition of Handbook of Practical Immunohistochemistry: Frequently Asked Questions continues to provide a comprehensive and yet concise state-of-the-art overview of the major issues specific to the field of immunohistochemistry. With links to the authors Immunohistochemical Laboratory website, this volume creates a current and up-to-date information system on immunohistochemistry. This includes access to tissue microarrays (TMA) of over 10,000 tumors and normal tissue to validate common diagnostic panels and provide the best reproducible data for diagnostic purposes.

Fully revised and updated from the first edition, the new features of the second edition include over 200 additional questions or revised questions with an IHC panel to answer each question; over 250 new color photos and illustrations; over 20 new useful biomarkers; hundreds of new references; several new chapters to cover phosphoproteins, rabbit monoclonal antibodies, multiplex IHC stains, overview of predictive biomarkers, and integration of IHC into molecular pathology; many new coauthors who are international experts in a related field; many updated IHC panels using Geisinger IHC data collected from over 10,000 tumors and normal tissues; and updated appendices containing detailed antibody information for both manual and automated staining procedures.

Comprehensive yet practical and concise, the Handbook of Practical Immunohistochemistry: Frequently Asked Questions, Second Edition will be of great value for surgical pathologists, pathology residents and fellows, cytopathologists, and cytotechnologists.



Fan Lin, MD, PhD

Geisinger Medical Center

Anatomic Pathology, Pathology and Laboratory Medicine

Danville, PA

Jeffrey Prichard, DO

Geisinger Medical Center

Anatomic Pathology, Pathology and Laboratory Medicine

Danville, PA


In a conceptually current, quick-reference, Question & Answer format, the second edition of Handbook of Practical Immunohistochemistry: Frequently Asked Questions continues to provide a comprehensive and yet concise state-of-the-art overview of the major issues specific to the field of immunohistochemistry. With links to the authors Immunohistochemical Laboratory website, this volume creates a current and up-to-date information system on immunohistochemistry. This includes access to tissue microarrays (TMA) of over 10,000 tumors and normal tissue to validate common diagnostic panels and provide the best reproducible data for diagnostic purposes.Fully revised and updated from the first edition, the new features of the second edition include over 200 additional questions or revised questions with an IHC panel to answer each question; over 250 new color photos and illustrations; over 20 new useful biomarkers; hundreds of new references; several new chapters to cover phosphoproteins, rabbit monoclonal antibodies, multiplex IHC stains, overview of predictive biomarkers, and integration of IHC into molecular pathology; many new coauthors who are international experts in a related field; many updated IHC panels using Geisinger IHC data collected from over 10,000 tumors and normal tissues; and updated appendices containing detailed antibody information for both manual and automated staining procedures.Comprehensive yet practical and concise, the Handbook of Practical Immunohistochemistry: Frequently Asked Questions, Second Edition will be of great value for surgical pathologists, pathology residents and fellows, cytopathologists, and cytotechnologists.

Fan Lin, MD, PhDGeisinger Medical CenterAnatomic Pathology, Pathology and Laboratory MedicineDanville, PAJeffrey Prichard, DOGeisinger Medical CenterAnatomic Pathology, Pathology and Laboratory MedicineDanville, PA

Chapter 1        Immunohistochemistry Quality Management and Regulation                         Jeffrey PrichardChapter 2        Standardization of Diagnostic Immunohistochemistry                        Fan Lin and Jianhui ShiChapter 3        Automated Immunohistochemistry Overview                        Jeffrey Prichard and Angela K. BittingChapter 4        Geisinger Immunohistochemical Antibodies and Staining Protocols                        Fan Lin, Jeffrey Prichard, Angela K. Bitting, Jianhui Shi, Haiyan Liu, Myra L.                               Wilkerson, Zongming E. ChenChapter 5        Immunohistochemistry: A Dako Perspective                        Ole Feldballe Rasmussen and Lars RudbeckChapter 6        Immunohistochemistry: Ventana Perspective                        Traci DeGeerChapter 7        Rabbit Monoclonal Antibodies                        Weimin Zhu, Aihua Li, Taiying ChenChapter 8        Immunohistochemical Detection of Phosphoproteins and Cancer Pathways                        Kerstin A. David and Hartmut JuhlChapter 9        Overview of Predictive Biomarkers and Integration of IHC into Molecular                                     Pathology                        Zongming E. Chen and Fan LinChapter 10      Tissue Microarray                        Myra L. Wilkerson and Stephen M. HewittChapter 11      Unknown Primary/Undifferentiated Neoplasm                        Fan Lin and Haiyan LiuChapter 12      Exfoliative Cytology and Effusions                        Steven C. Meschter and Jan F. SilvermanChapter 13      Breast                        Haiyan LiuChapter 14      Predictive Biomarkers in Breast Cancer:  ER, PR and Her-2/neu                        Jeffrey Prichard, David G. Hicks, M. Elizabeth H. HammondChapter 15      Central Nerve System                        Syed A. Jaffar Kazmi, Hope Hueizhi Wu, Conrad SchuerchChapter 16      Thyroid, Parathyroid and Adrenal Glands                        Haiyan Liu, Myra L. Wilkerson, Fan LinChapter 17      Salivary Glands and Head and Neck                        Conrad Schuerch and Shaobo ZhuChapter 18      Pleuropulmonary and Mediastinal Neoplasms                        Kai Zhang, Hongbing Deng, Philip T. CagleChapter 19      Uterus                        Hanna G. Kaspar and Christopher P. CrumChapter 20      Ovary                        Jeffrey Prichard and Hanna G. KasparChapter 21      Prostate Gland                        Haiyan Liu, Fan Lin, Qihui “Jim” ZhaiChapter 22      Urinary Bladder and Urachus                        Myra L. Wilkerson and Liang ChengChapter 23      Kidney                        Fan Lin and Ximing J. YangChapter 24      Testis and Paratesticular Tissues                        Myra L. Wilkerson and Liang ChengChapter 25      Pancreas and Ampulla                        Fan Lin and Hanlin L. WangChapter 26      Liver, Bile Ducts and Gallbladder                        Zongming E. Chen, Jeffrey Prichard and Fan LinChapter 27      Upper Gastrointestinal Tract                        Jinhong Li and Fan LinChapter 28      Lower Gastrointestinal Tract                        Zongming E. Chen, Jinhong Li, Fan LinChapter 29      Soft Tissue and Bone Tumors                        Shaobo Zhu, Markku M. Miettinen, George LinChapter 30      Lymph Node                        Xiaohong (Mary) Zhang and Nadine S. AguileraChapter 31      Bone Marrow                        R. Patrick Dorion and Xiaohong (Mary) ZhangChapter 32      Infectious Diseases                        Dirk M. Elston, Lawrence E. Gibson, Heinz KutznerChapter 33      Skin                        Tammie FerringerChapter 34      Application of Direct Immunofluorescence for Skin and Mucosal Biopsies:                        A Practical Review                        William B. TylerChapter 35      Application of Fluorescent in Situ Hybridization (FISH) in Surgical and Cytologic                        Specimens                        (Solid Tumors, Hematopoietic Tumors, Urine, Bile Duct Brushing and                                            Bronchoscopy)                        Hong Yin, Barbara V. Paynton, Michele Kay Zelonis, Dana Snyder, Nefize Sertac                        Kip

Erscheint lt. Verlag 21.2.2015
Zusatzinfo XV, 764 p. 465 illus., 461 illus. in color.
Verlagsort New York
Sprache englisch
Themenwelt Medizin / Pharmazie Gesundheitsfachberufe
Medizin / Pharmazie Medizinische Fachgebiete
Studium 2. Studienabschnitt (Klinik) Pathologie
ISBN-10 1-4939-1578-9 / 1493915789
ISBN-13 978-1-4939-1578-1 / 9781493915781
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