Clinical Tuberculosis

Lloyd N. Friedman, M.D., is a Clinical Professor of Pulmonary, Critical Care and Sleep Medicine at the Yale School of Medicine, New Haven, CT. He is Director of Inpatient Quality and Safety for the Department of Internal Medicine. He is a member of the American Thoracic Society, a member of the Society of Critical Care Medicine, a fellow of the American College of Chest Physicians and a member of the International Union Against Tuberculosis and Lung Disease. He is Chairman of the Connecticut Tuberculosis Elimination Advisory Committee. Martin Dedicoat PhD, FRCP, BSc, DTM&H is a Consultant physician in infectious diseases at the University Hospitals Birmingham. He is currently clinical lead for tuberculosis for Birmingham and Solihull, UK. His main research interests center around tuberculosis transmission in urban settings. Dr Dedicoat is a member of the British Thoracic Society drug resistant tuberculosis management group advising on management of complex tuberculosis patients across the UK. He also sits on the National Tuberculosis board for England. Dr. Peter D. O. Davies graduated in 1966 from Marlborough College, Wilts, UK and obtained his BM, BCh and MA from University College, Oxford, UK in 1971 and St. Thomas’s Hospital in London in 1973. He gained a DM from oxford in 1984. He was a Consultant General and Respiratory Physician at Aintree University Hospital from 1988 to 2011 and at Liverpool Heart Chest Hospital from 1988 to 2015. He is or has been a member of the British Medical Association, the British Thoracic Society, the European Respiratory Society, the Royal College of Physicians of London (Fellow), the Royal Society of Medicine, the American Thoracic Society, the North Western Society of Respiratory Physicians where he served as President in 2007, the International Union Against Tuberculosis and Lung Disease where he was Chair of the Tuberculosis Section, President of the European section, and Editor in Chief of the International Journal of Tuberculosis and Lung Disease, and a member of NICE where he was chair of the Tuberculosis Section. He co-founded the UK Based TB charity in 1998. Dr. Davies is an expert in tuberculosis and edited the inaugural edition of the textbook, Clinical Tuberculosis in 1994 and has continued as editor for the subsequent 5 editions.

Foreword. Preface. Editors. Contributors. I. BACKGROUND. The History of Tuberculosis from Earliest Times to the Development of Drugs. Epidemiology. II. PATHOLOGY AND IMMUNOLOGY. Mycobacterium tuberculosis: The Genetic Organism. Pathogenesis of Tuberculosis. III. TRANSMISSION. Using Genotyping and Molecular Surveillance to Investigate Tuberculosis Transmission. Tuberculosis Transmission Control. IV. DIAGNOSIS OF ACTIVE DISEASE AND LATENTINFECTION. Diagnosis of Active Pulmonary Tuberculosis. Radiology of Mycobacterial Disease. Diagnosis of Latent TB Infection. V. DRUGS AND VACCINES FORTUBERCULOSIS. Clinical Pharmacology of the Anti-Tuberculosis Drugs. New Developments in Drug Treatment. BCG and Other Vaccines. VI. CLINICAL ASPECTS AND TREATMENT. Pulmonary Tuberculosis. Extrapulmonary Tuberculosis. Tuberculosis and Human Immunodeficiency Virus Coinfection. Drug-Resistant Tuberculosis. The Surgical Management of Tuberculosis and Its Complications. Tuberculosis in Childhood and Pregnancy. Treatment of Latent Tuberculosis Infection Including Risk Factors for the Development of Tuberculosis. VII. OFFICIAL STATEMENTS: COMPARISON OF NATIONAL AND INTERNATIONAL RECOMMENDATIONS. Treatment Guidelines for Active Drug-Susceptible and Drug-Resistant Pulmonary Tuberculosis, and Latent Tuberculosis Infection. VIII. CONTROL. Tuberculosis Epidemic Control: A Comprehensive Strategy to Drive Down Tuberculosis. IX. RELATED ASPECTS. Animal Tuberculosis. Index.