Annual Reports on NMR Spectroscopy (eBook)

Cover 1
Contents 10
List of Contributors 6
Preface 8
Chapter 1. A Study of Conformational Stability of Polypeptide Blends by Solid State NMR Spectroscopy 12
1. Introduction 13
2. Polypeptide blend preparations 19
3. 13C CP/MAS NMR spectral analysis and conformational characterization of homopolypeptides and their blends 21
4. 1HT1pS of homopolypeptides and their blend compatibility 38
5. Two-dimensional 13C–1H Hetcor spectral analysis and structural characterization of polypeptides blends 50
6. Conclusions 65
References 65
Chapter 2. Applications of Heteronuclear X/Y-Correlation Spectroscopy in Organometallic and Organoelement Chemistry: Recent Developments 70
1. Introduction 71
2. Methods 73
3. Recent applications of X/Y correlations 98
4. Conclusions 110
References 111
Chapter 3. NMR Studies of Biomolecular Dynamics and Structural Plasticity Using Residual Dipolar Couplings 116
1. Introduction 117
2. Theoretical background 120
3. Molecular alignment 134
4. Applications to protein domains 145
5. Protein dynamics at the local level 152
6. Applications to RNA 163
7. Applications to oligosaccharides 168
8. Conclusions and future perspectives 170
Acknowledgements 171
References 172
Chapter 4. Advances in Theoretical and Physical Aspects of Spin–Spin Coupling Constants 178
1. Introduction 179
2. Calculation and analysis of spin–spin coupling constants 182
3. Coupling mechanisms and factors affecting them 195
Acknowledgements 259
References 259
Chapter 5. High Resolution Magic Angle Spinning – Applications to Solid Phase Synthetic Systems and Other Semi-Solids 272
1. Introduction 272
2. Nature of the samples 274
3. Specialized NMR techniques 279
4. Applications to polymer-supported species 283
5. Applications to polymers, whole cells and tissues 290
6. Summary and prospects 297
References 298
Index 308