Human Cataract Formation (eBook)

Jonathan Nugent is the editor of Human Cataract Formation, published by Wiley. Julie Whelan is the editor of Human Cataract Formation, published by Wiley.

Human cataract formation 5
Contents 7
Introduction 13
Classification of human cataractous change by the American Cooperative Cataract Research Group method 15
Discussion 29
Epidemiological and other studies in the assessment of factors contributing to cataractogenesis 37
Discussion 52
Oxidation and cataract 60
Discussion 67
Metabolism and function of glutathione in the lens 77
Discussion 95
Cataracts and photochemical damage in the lens 100
Discussion 111
Diabetic and galactosaemic cataracts 122
Discussion 135
Calcium and the physiology of cataract 144
Discussion 162
General discussion Causes and mechanisms of human cataract formation 167
Cytoskeletal proteins of the ageing human lens 177
Discussion 188
Interaction of crystallins with M. Vermorken, I. Dunia and E. L. Benedetti the cytoskeletal-plasma membrane complex of the bovine lens 191
Discussion 202
Crystallin genes: templates for lens transparency 207
Discussion 220
The crystallin gene families 224
The molecular structures and interactions of bovine and human Y- crystallins 235
Discussion 246
The molecular basis of cataract formation 253
Discussion 256
The application of non-invasive techniques to the study of cataract development on the metabolic and the protein molecular level 264
Discussion 275
Final general discussion Sequence of events in cataract formation 282
Strategies for future research on the human lens 287
Index of contributors 291
Subject index 293