Quality of Life (eBook)

Peter Fayers, Emeritus Professor of Medical Statistics, University of Aberdeen, UK; Norwegian University of Science and Technology (NTNU), Trondheim, Norway. David Machin, Emeritus Professor of Clinical Trials Research, University of Sheffield, UK and Emeritus Professor of Clinical Statistics, University of Leicester.

Preface to the third edition

Preface to the second edition

Preface to the first edition

List of abbreviations

Part 1: Developing and Validating Instruments for Assessing Quality of Life and Patient-Reported Outcomes

1 Introduction

2 Principles of measurement scales

3 Developing a questionnaire

4 Scores and measurement: validity, reliability, sensibility

5 Multi-item scales

6 Factor analysis and structural equation modelling

7 Item response theory and differential item functioning

8 Item banks, item linking and computer-adaptive tests

Part 2: Assessing, Analysing and Reporting Patient-Reported Outcomes and the Quality of Life of Patients

9 Choosing and scoring questionnaires

10 Clinical trials

11 Samples sizes

12 Cross-sectional analysis

13 Exploring longitudinal data

14 Modelling longitudinal data

15 Missing data

16 Practical and reporting issues

17 Death and quality-adjusted survival

18 Clinical interpretation

19 Biased reporting and response shift

20 Meta-analysis

Appendix 1: Examples of instruments

Appendix 2: Statistical tables

References

Index