Advances in Heterocyclic Chemistry (eBook)

Cover 1
Contents 6
Contributors 8
Preface 10
Chapter 1. Synthesis and Properties of Acetylenic Derivatives of Pyrazoles 12
I. Introduction 13
II. Synthesis of Acetylenylpyrazoles 14
III. Chemical Properties of Acetylenylpyrazoles 43
IV. Structure, Spectra, and Properties of Acetylenylpyrazoles 80
V. Biological Properties of Acetylenylpyrazoles 93
VI. Conclusion 99
VII. Index of Tables 100
References 102
Chapter 2. Recent Advances in the Chemistry of 1-Hydroxyindoles, 1-Hydroxytryptophans, and 1-Hydroxytryptamines 112
I. Introduction 113
II. Synthetic Method for 1-Hydroxyindoles, 1-Hydroxytryptophans, and 1-Hydroxytryptamines 115
III. Physical Properties of 1-Hydroxyindoles, 1-Hydroxytryptophans, and 1-Hydroxytryptamines 119
IV. Chemical Reactions of 1-Hydroxy-, 1-Alkoxy-, and 1-( alpha-D-Glucopyranosyl)indoles 120
V. Synthetic Studies toward Novel Heterocyclic Compounds and Natural Products 149
VI. Studies toward Biologically Active 1-Hydroxyindole Derivatives 157
VII. Summary 159
VIII. Natural Products and Some Notes 160
References 161
Chapter 3. Diacetylene and Its Derivatives in Heterocyclization Reactions 168
I. Introduction 169
II. Reactions of Diacetylene 170
III. Reactions of 1-Heterobut-1-en-3-ynes 194
IV. Reactions of 4-Heterobut-3-en-2-ones 221
V. Reactions of 4-Aminobut-3-yn-2-ones 248
VI. Conclusion 261
References 261
Chapter 4. 1,2,4-Triazine N-Oxides 272
I. Introduction 272
II. Molecular Spectra 273
III. Chemical Properties 277
IV. Methods for the Synthesis of 1,2,4-Triazine N-Oxides 302
V. Conclusion 311
References 312