Chemical Warfare Agents (eBook)

Timothy C. Marrs OBE. Edentox Associates, Edenbridge, Kent, UK; National Poisons Information Service Birmingham Centre, City Hospital, Birmingham, UK; University of Central Lancashire, Preston, UK. Robert L. Maynard CBE. Air Pollution Unit, Health Protection Agency, London, UK. Frederick R. Sidell i. Institute of Chemical Defense, Aberdeen Proving Ground, Maryland, USA.

Chemical Warfare Agents Toxicology and Treatment 3
Contents 7
List of Contributors 9
Preface 13
1 Opinions of Chemical Warfare 15
2 The Physicochemical Properties and General Toxicology of Chemical Warfare Agents 35
3 Dispersion and Modelling of the Spread of Chemical Warfare Agents 81
4 The Fate of Chemical Warfare Agents in the Environment 103
5 Biological Markers of Exposure to Chemical Warfare Agents 141
6 Respiratory Protection 171
7 Responding to Chemical Terrorism: Operational Planning and Decontamination 189
8 Toxicology of Organophosphate Nerve Agents 205
9 A History of Human Studies with Nerve Agents by the UK and USA 237
10 Nerve Agents: Low-Dose Effects 255
11 Managing Civilian Casualties Affected by Nerve Agents 263
12 The Management of Casualties Following Toxic Agent Release: The Approach Adopted in France 275
13 The Dark Morning: The Experiences and Lessons Learned from the Tokyo Subway Sarin Attack 291
14 Atropine and Other Anticholinergic Drugs 301
15 Oximes 319
16 The Use of Benzodiazepines in Organophosphorus Nerve Agent Intoxication 345
17 Pretreatment for Nerve Agent Poisoning 357
18 Gulf War Syndrome 369
19 Mustard Gas 389
20 Dermal Aspects of Chemical Warfare 423
21 Sulphur Mustard Injuries of the Skin: Pathophysiology and Clinical Management of Chemical Burns 437
22 The Normal Bone Marrow and Management of Toxin-Induced Stem Cell Failure 457
23 Organic Arsenicals 481
24 Phosgene 491
25 Cyanides: Chemical Warfare Agents and Potential Terrorist Threats 509
26 Riot Control Agents in Military Operations, Civil Disturbance Control and Potential Terrorist Activities, with Particular Reference to Peripheral Chemosensory Irritants 557
27 Ricin and Abrin Poisoning 627
28 The Total Prohibition of Chemical Weapons 647
29 An A–Z of Compounds of Interest in Relation to Chemical Warfare and Other Malevolent Uses of Poisons 677
Index 723

"...exceptionally informative and comprehensive, easy to read, and
well organized. It is an invaluable reference for any professional
involved in the field." (Journal of Chemical Health and
Safety)

"It is a sad reflection of the days in which we live that the
second edition of this book is needed, but needed it is. This text
surely is the most comprehensive guide to the whole topic of
chemically related terrorist incidents.... An excellent book to be
thoroughly recommended to those involved in the assurance of public
health and for everyone involved in toxicology in general." (The
Bulletin, The Royal College of Pathologists, January 2008)

"...a very good source document and is recommended for the
professional library." (The ASA Newsletter, October 19,
2007)

"...an excellent resource..." (CHOICE, October 2007)

"...a solid comprehensive piece of work, thoroughly researched
and ideal as a reference book..." (The British Toxicology
Society Newsletter, Winter 2007)